From Molecule to Meaning, with Super Soft Ionization
Clean, fragmentation-free spectra even at trace levels | Real-time, high-throughput analysis of vapors and nano-aerosols
Detect and identify unknowns, beyond existing databases | Seamless LC-MS and GC integration.
“FIT’s ecosystem has you covered, from sampling to data analysis, so you can focus on science.”
Volatilomic Products
Super soft ionization for data quality and interpretability. Real-time, high-throughput for statistical significance. Full automatic control for reproducibility.
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Standardized breath interface for real-time and offline analysis. Guides and logs flow and CO2 for reproducible results. Compact and easy to use.
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Streamlines SESI-MS data analysis, from peak detection to cohort comparison. Peak
alignment, isotopic clustering, export tools, and more. No coding required.
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Storage and transfer of VOCs and nano-aerosols for offline SESI-MS. Nalophan membrane in stainless steel. Temperature-controlled and logging for sample integrity.
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Carrying gas for Super SESI analysis. Clean, regulated flow for low background and reproducibility. Humidity control for consistent results.
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Collects a predefined exhalation fraction for offline SESI-MS breath analysis (based on exhaled volume and CO2 thresholds). Compatible with STABILION and EXHALION.
Swirling flow enhances evaporation for real-time headspace SESI-MS. Interfaces with SIROCCO and Super SESI. Click-in connections for high-throughput operation.
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Legacy SESI source for real-time vapor ionization. Actively supported for giving a new purpose to your existing Thermo Exactive system.
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Applications
Breath analysis in real time
Dynamic Headspace Analysis
Offline Breath analysis
Headspace High throughput
Nose-space analysis
SUPER SESI, EXHALION,
Nose-space adaptor
Aerosol and smoke analysis
SUPER SESI,
Aerosol adaptor
Offline Trace detection
GC - SESI -MS
SUPER SESI,
GC adaptor
Customer Success
Dr. Prof. Patrik Španěl - J. Heyrovsky Institute of Physical Chemistry of the CAS, Prague, Czech Republic
“The SSX ion source is surely a masterpiece of state of the art engineering. Full understanding of the ion chemistry occurring between the ESI generated ions and VOC molecules inside will be an interesting challenge to tackle.”
Prof. Dr. med. Malcolm Kohler - University Hospital Zurich (USZ), Switzerland.
“We observed significant changes in glyoxylate and dicarboxylate, tricarboxylic acid cycle (TCA), and tryptophan metabolic pathways. Our findings suggest that continuous monitoring of metabolite shifts from exhaled air should focus on monitoring platforms dedicated to volatile and slightly volatile metabolites”
Dr. Prof. Jangjiang Zhu - The Ohio State University, Ohio, USA.
“Our results suggested that the optimized SESI-HRMS method can be suitable forthe analysis of VFAs from gut microbes in a rapid, sensitive, and non-invasive manner.”
Dr. Prof. Renato Zenobi - ETH Zurich, Switzerland
“When SESI is combined with state-of-the-art mass spectrometers, low limits of detection (pptv) are achievable without any sample pre-concentration. We exploit this feature in our lab in a number of projects which require fast mass spectrometric analysis of vapors at trace concentrations.”
Dr. Prof. Xue Li - Jinan University, Guangzhou, China.
““IAV infection induces a cascade of metabolite alterations, some of which are excreted via the skin and breath to the ambient air. Such IAV-induced odor traits could be captured by SESI-HRMS by simply dragging the air surrounding the infected mice into the analyzer. The process is non-invasive and rapid, as it requires no sample manipulation.”
Dr. Prof. Pablo Sinues - University Children’s Hospital Basel, University of Basel, Switzerland
“We use SESI-HRMS to sense exhaled molecules at minute concentrations. Since the analysis requires no sample-preparation or manipulation, the diagnostic result can be obtained nearly in real-time. This technology is especially well suited for children due to its non-invasive nature”
Dr. Prof. Lars M. Blank - Institute of Applied Microbiology at RWTH Aachen University
“Thank you Fossiliontech for all your support.”