Blog
Meet us at DIFFA26 in Freising | 14-16 October
Fossiliontech will participate in DIFFA26 - Direct Injection Food Flavour Analytics, an international symposium focused on real-time food-flavour analytics and direct injection mass spectrometry.
Visit us at our booth to learn more about our Super SESI-Orbitrap solutions for real-time volatilomics, food and flavour analysis, and don’t miss our CEO, Guillermo Vidal-de-Miguel, who will give the talk “Expanding molecular coverage in food and flavour analysis with SESI-Orbitrap” on Wednesday, 14 October, at 16:30.
We look forward to connecting with you in Freising.
Meet us at IMSC 2026 in Lyon | 22-28 August
Fossiliontech will participate in the International Mass Spectrometry Conference, IMSC 2026, held in Lyon, France, from 22 to 28 August.
Come visit us at our booth and stop by poster POC_0151 to discover our latest technologies for direct VOC analysis, real-time volatilomics, Super SESI-Orbitrap applications and controlled offline breath sampling with STABILION.
We look forward to seeing you in Lyon.
Meet us at CAI2026 in Salamanca | 21-24 July
Fossiliontech will participate in the 1st Congress of Instrumental Analysis, CAI2026, a multidisciplinary meeting dedicated to advanced analytical technologies and their applications.
Visit us at our booth and stop by poster P2-106 to learn more about our solutions for real-time volatilomics and Super SESI-Orbitrap analysis. We will also host a live demo at our laboratory, showcasing the Fossiliontech portfolio across breath analysis, flavor compounds, headspace analysis and VOC monitoring.
We hope to see you there.
Meet us at SUMS Demo Day in Stanford | 1 April 2026
Fossiliontech will present and install its volatilomics technologies during the SUMS New Tech Demo Day, hosted at the SUMS laboratory in Stanford.
During the session, our team will carry out the on-site installation of the Super SESI-X volatile analysis ion source, along with additional volatilomics equipment, showcasing their application in a real laboratory environment.
Participants will have the opportunity to learn more about our latest volatile analysis technologies and follow sample demonstrations, including headspace, flavor compounds, breath, and perfume analyses.
We invite you to join us.
Download the presentation here
Meet us at Orbitrap Day in Paris | 6 November 2025
Fossiliontech will present its technologies at the Orbitrap Day in Paris, which will be held at the Institut Pasteur.
Using Super Soft ionization, Orbitrap instruments can resolve most volatilomics samples directly, without the need for GC, enabling higher throughput and dynamic studies.
We look forward to participating in the event and engaging with the scientific community.
Meet us at IABR Breath Summit in Innsbruck | 14–19 September
Fossiliontech will attend the IABR Breath Summit 2025, taking place from September 14 to 19, 2025, in Innsbruck, Austria.
This international summit brings together researchers and industry experts focused on breath analysis and related analytical technologies. It is a great opportunity to exchange ideas, discuss current challenges, and explore new developments in the field.
Meet us at ASMS 2025 in Baltimore | 1-5 June
The 73rd Conference on Mass Spectrometry and Allied Topics – ASMS 2025 will take place in Baltimore (Maryland, USA), and we will be attending as exhibitors!
We are looking forward to meeting you at our booth to discuss the newest topics in Mass Spectrometry.
Meet us at ASMS 2024 in Anaheim | 2-6 June
The 72nd Conference on Mass Spectrometry and Allied Topics - ASMS 2024 will take place in Anaheim (California- USA), and we are attending as exhibitors!
We are looking forward to meeting you at booth 253 to discuss the newest topics of Mass Spectrometry.
Meet us at IABR in Indianapolis | 3-6 June
We are glad to announce that we will be at the next IABR Breath Summit 2024 Conference in Indianapolis, USA!
Breath analysis is a rapidly evolving field thanks to the continuous improvement of analytical instruments and sensor technologies, which are both supported by sophisticated data analysis techniques to reach the goal of completely non-invasive personal monitoring of health conditions and diagnosis of diseases.
We will be there discussing the latest breath-related research, and looking forward to meeting the Breath Research community again! Don't miss it!
Real-Time Volatile Metabolomics Analysis of Dendritic Cells
Dendritic cells (DCs) actively sample and present antigen to cells of the adaptive immune system and are thus vital for successful immune control and memory formation. Immune cell metabolism and function are tightly interlinked, and a better understanding of this interaction offers potential to develop immunomodulatory strategies. However, current approaches for assessing the immune cell metabolome are often limited by endpoint measurements, may involve laborious sample preparation, and may lack unbiased, temporal resolution of the metabolome. In this study, we present a novel setup coupled to a secondary electrospray ionization-high resolution mass spectrometric (SESIHRMS) platform allowing headspace analysis of immature and activated DCs in real-time with minimal sample preparation and intervention, with high technical reproducibility and potential for automation.
Online breath analysis with SUPER SESI - HRMS for metabolic signatures in children with allergic asthma
Improving the diagnosis and management of pediatric asthma is necessary. Breath analysis can help by assessing altered metabolism and disease-associated processes in a non-invasive manner. This study aimed to identify exhaled metabolic signatures using SUPER SESI - HRMS that can distinguish children with allergic asthma from healthy controls.
Monitoring kinetics of tobacco metabolites by breath analysis
This application note highlights the potential of breath analysis in providing valuable insights into the exposure of lungs and the absorption of molecules directly into the bloodstream. The SUPER SESI - QExactive HF -EXHALION system was utilized for breath sample analysis, which recorded a volunteer's breath for 20 minutes after smoking a cigarette. The study captured insights into the kinetics of tobacco metabolites. This approach underscores the capability of breath analysis to provide real-time and valuable data on substance metabolism and exposure. It showcases a significant step forward in non-invasive diagnostic methodologies.
Prediction of systemic free and total valproic acid by off-line analysis of exhaled breath in epileptic children and adolescents
This study explores breath analysis as a tool for therapeutic drug monitoring (TDM) in clinical settings, focusing on valproic acid (VPA) in epilepsy treatment. It contrasts real-time and off-line mass spectrometry methods for analyzing exhaled compounds associated with VPA. Real-time analysis involves direct exhalation into a mass spectrometer, while off-line analysis uses a gas collection device.
Meet us at BMSS in Birmigham | 1 Februray
Fossiliontech will be at the BMSS Ambient Ionization event on February 1, 2024, at ThinkTank, Birmingham.
We are looking forward to meeting you there. Join us to discover the latest in mass spectrometry and our electrospray ionization technology.
Rapid detection of S.aureus and S.pneumoniae by real-time analysis of volatile metabolites
Early detection of pathogenic bacteria is needed for rapid diagnostics allowing adequate and timely treatment of infections. In this study, we show that secondary electrospray ionization–high resolution mass spectrometry (SESI-HRMS) can be used as a diagnostic tool for rapid detection of bacterial infections as a supportive system for current state-of-the-art diagnostics.
SESI-HRMS job opening at Diagnose Eary in the Bay Area
We are thrilled to announce a fantastic job opening at Diagnose Early (www.diagnoseearly.com), a pioneer in advanced technological research. Thanks to recent strategic investments, including the acquisition of several state-of-the-art SUPER SESI - Orbitrap breath analysis machines, DE is at the forefront of biomarker identification research.
www.fossiliontech
Analysis of Volatile Compounds in Garlic, Onion, and Ramsons using SUPER SESI-HRMS
In this study, SUPER SESI-Orbitrap MS was used to analyze the time-resolved gas-phase volatile organic compounds (VOCs) of garlic, ramsons, and onion.
The aim of this study was to address the difficulties of characterizing heat-labile sulfur molecules from various Allium spp. In this, we will delve into the analytical method SUPER SESI-HRMS used in this study and its applications in the analysis of volatile compounds in garlic, onion, and ramsons.
Drug Pharmacokinetics Determined by Real-Time Analysis of Mouse Breath
SUPER SESI-HRMS was used to non-invasively and in real-time monitor the pharmacokinetics of ketamine, propofol, and valproic acid, along with their metabolites in mice. This approach allowed for obtaining real-time pharmacokinetic curves without the need to sacrifice the animals, representing a significant advance in terms of animal welfare and time and cost savings.
4th European Single Cell Proteomics (ESCP) Conference
A couple of weeks ago, my colleague Jamil from Fossiliontech attended the Single Cell Proteomics meeting (ESCP, Vienna 2023) and I want to share his notes with you.
I hope this summary will be useful for you :)
Single Cell Analysis: Why?
This technique is essential for understanding cell variability and how it can be applied in diagnostics, personalized therapies, and medical advances.
What technical Challenges need to be addressed?:
FossilionTech in Paris: In Vitro and In Vivo Analyses of VOCs in Food Demo at ThermoFisher Laboratories
A few days ago, we attended a demonstration organized by FossilionTech in the laboratories of Thermo Fisher Scientific in Paris. The performance of the SUPER SESI X-Orbitrap Exploris 120 in the in vitro and in vivo analysis of volatile organic compounds (VOCs) present in food was showcased. The primary goal of this event was to demonstrate the ability of SUPER SESI X-ORBITRAP MS to detect and monitor Volatile Organic Compounds (VOCs) in food, emphasizing the importance of incorporating this technology into food production processes for a deeper understanding of the aromas and flavors of food. Additionally, it highlights the significant improvements in food safety that can be achieved through the adoption of this technology.

