SESI-HRMS reveals tryptophan pathway metabolites in exhaled human breath

SESI-HRMS reveals tryptophan pathway metabolites in exhaled human breath

D. García-Gómez, T. Gaisl, L. Bregy, P. M-L Sinues, M. Kohler and R. Zenobi

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Abstract

Many studies and personalized medicine in general require frequent measurements and/or rapid results of biomarker levels. Here we show that 20 low volatility metabolites of the tryptophan pathway can be detected in exhaled human breath. This real-time and noninvasive method offers an attractive alternative to blood analysis.

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