SESI-HRMS reveals tryptophan pathway metabolites in exhaled human breath
D. García-Gómez, T. Gaisl, L. Bregy, P. M-L Sinues, M. Kohler and R. Zenobi
Many studies and personalized medicine in general require frequent measurements and/or rapid results of biomarker levels. Here we show that 20 low volatility metabolites of the tryptophan pathway can be detected in exhaled human breath. This real-time and noninvasive method offers an attractive alternative to blood analysis.