2008

Secondary Electrospray Ionization (SESI) of Ambient Vapors for Explosive Detection at Concentrations Below Parts Per Trillion

Secondary Electrospray Ionization (SESI) of Ambient Vapors for Explosive Detection at Concentrations Below Parts Per Trillion

P. M-L Sinues, J. Rus, G. F. de la Mora, M. Hernández, and J. F. de la Mora

We determine the sensitivity of several commercial atmospheric pressure ionization mass spectrometers towards ambient vapors, ionized by contact with an electrospray of acidified or ammoniated solvent, a technique often referred to as secondary electrospray ionization (SESI).

Neutral desorption sampling of biological surfaces for rapid chemical characterization by extractive electrospray ionization mass spectrometry

Neutral desorption sampling of biological surfaces for rapid chemical characterization by extractive electrospray ionization mass spectrometry

H. Chen, R. Zenobi

Extractive electrospray ionization mass spectrometry (EESI-MS) allows the real-time, direct analysis of complex gaseous and liquid samples without any sample pretreatment under ambient conditions. By using a neutral desorption (ND) sampling gas beam to gently impact a surface, the analyte present on a surface can be efficiently sampled and then transported …

Direct Analysis of Fatty Acid Vapors in Breath by Electrospray Ionization and Atmospheric Pressure Ionization-Mass Spectrometry

Direct Analysis of Fatty Acid Vapors in Breath by Electrospray Ionization and Atmospheric Pressure Ionization-Mass Spectrometry

P. M-L Sinues, J. F. de la Mora

Real time analysis of human breath is achieved in an atmospheric pressure ionization mass spectrometer (API-MS) by negatively charging exhaled vapors via contact with an electrospray cloud. The spectrum observed is dominated by a wide range of deprotonated fatty acids, including saturated chains up to C14. Above C14, the background from cutaneous sources becomes dominant.

Real-time, on-line monitoring of organic chemical reactions using extractive electrospray ionization tandem mass spectrometry

Real-time, on-line monitoring of organic chemical reactions using extractive electrospray ionization tandem mass spectrometry

L. Zhu, G. Gamez, H. W. Chen, H. X. Huang, K. Chingin and Renato Zenobi

Extractive electrospray ionization mass spectrometry (EESI-MS) for real-time monitoring of organic chemical reactions was demonstrated for a well-established pharmaceutical process reaction and a widely used acetylation reaction in the presence of a nucleophilic catalyst, 4-dimethylaminopyridine (4-DMAP) …

Rapid classification of perfumes by extractive electrospray ionization mass spectrometry (EESI-MS)

Rapid classification of perfumes by extractive electrospray ionization mass spectrometry (EESI-MS)

K. Chingin, G. Gamez, H. Chen, L. Zhu and R. Zenobi

Extractive electrospray ionization mass spectrometry (EESI-MS) was applied to rapid fingerprinting of various perfumes for quality classification. Unique EESI-MS fingerprints of ten famous brands were obtained. This technique was shown to be applicable to rapid forgery detection on the example of an authentic and a counterfeit ‘Miss Dior’ fragrance by Christian Dior.