In vivo monitoring of volatile metabolic trajectories enables rapid diagnosis of influenza A infection

Zhihong Yin, Wenbo Huang, Kapil Dev Singh, Zhaoming Chen, Xing Chen, Zhen Zhou, Zifeng Yang, Pablo Sinues and Xue Li

In vivo monitoring of volatile metabolic trajectories enables rapid diagnosis of influenza A infection.png

Abstract:

We report that influenza A virus infection induces changes in odor traits that could be captured by real-time high-resolution mass spectrometry in a living mouse model. The most striking changes in the volatile metabolites may be associated mostly to glyoxylate/dicarboxylate metabolism.

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Real-time (on-line) chemical characterisation of thermal aerosols by super secondary electrospray ionization coupled with high-resolution mass spectrometry (Super SESI-HRMS)

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Validation of breath biomarkers for obstructive sleep apnea