2010

Evaluation of extractive electrospray ionization and atmospheric pressure chemical ionization for the detection of narcotics in breath

Evaluation of extractive electrospray ionization and atmospheric pressure chemical ionization for the detection of narcotics in breath

C. Berchtold, L. Meier, R. Zenobi 

Diagnosis by online breath analysis using mass spectrometry is challenging because of the low concen-trations of pertinent compounds in breath. Here we investigate extractive electrospray ionization and atmospheric pressure chemical ionization for the detection of narcotics in breath.

Fast Detection of Volatile Organic Compounds from Bacterial Cultures by Secondary Electrospray Ionization-Mass Spectrometry

Fast Detection of Volatile Organic Compounds from Bacterial Cultures by Secondary Electrospray Ionization-Mass Spectrometry

J. Zhu, H. D. Bean, Y-M Kuo, and J. E. Hill

We propose a novel application of secondary electrospray ionization-mass spectrometry (SESI-MS) as a real-time clinical diagnostic tool for bacterial infection. It is known that volatile organic compounds (VOCs), produced in different combinations and quantities by bacteria as metabolites, generate characteristic odors for certain bacteria.

Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry

Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry

Liang Zhu, Zhong Hu, G. Gamez, Wai Siang Law, Huan Wen Chen, ShuiPing Yang, Konstantin Chingin, Roman M. Balabin, Rui Wang, TingTing Zhang, R. Zenobi

By gently bubbling nitrogen gas through beer, an effervescent beverage, both volatile and non-volatile compounds can be simultaneously sampled in the form of aerosol. This allows for fast (within seconds) fingerprinting by extractive electrospray ionization mass spectrometry (EESI-MS) in both negative and positive ion mode, without the need for any sample pre-treatment …

Sampling analytes from cheese products for fast detection using neutral desorption extractive electrospray ionization mass spectrometry

Sampling analytes from cheese products for fast detection using neutral desorption extractive electrospray ionization mass spectrometry

Zhongchen Wu, Konstantin Chingin, Huanwen Chen, Liang Zhu, Bin Jia, R. Zenobi

The development of analytical techniques suitable for sensitive, high-throughput, and nondestructive food analysis has been of increasing interest in recent years. In this study, mass-spectral fingerprints of various cheese products were rapidly recorded in the mass range of m/z 50-300 Da without any sample pretreatment, using ND-EESI-MS in negative ion mode.