Noninvasive Disease Diagnostics: The Swiss Contribution Highlights to Breath Analysis Research
S.J. Swift, K. Dryahina, P. Španěl, F. Kontopidou, C. Kokkotis, R.Zenobi, S. Giannoukos
Abstract
Breath analysis in Switzerland: advancing real-time, noninvasive clinical diagnostics
Breath analysis is emerging as a powerful, noninvasive approach to clinical diagnostics, with Switzerland at the forefront of recent advances. This perspective highlights progress since 2019, focusing on secondary electrospray ionization high-resolution mass spectrometry (SESI-HR-MS) for real-time metabolic profiling. By identifying key methodological gaps and clinical challenges, it outlines the path toward translating breath analysis into routine clinical practice and precision medicine.