Size matters

Size matters, but why? Discover 3 reasons why this is the case in mass spectrometry proteomics ionization with electrospray.
This video is part of an educational series dedicated to improving the stability of the electrospray.

Why does the electrospray have to be so small?

In this video I will give you three reasons why the electrospray meniscus has to be so small. In the end, I will show you why the inner diameter of the emitter is irrelevant.

ESI stands for Electro-Spray Ionization. Ionization efficiency and ionization stability are important in mass spectrometry because the quality of the data depends on the quality of the spraying. Electrospray and nanoelectrospray are used for proteomics and metabolomics. Scientists and analytical chemists invest a lot of their time to obtain stable sprays.

I made and filmed an electrospray to show what it does when it is stable and what happens when it is unstable. This video is a practical introduction to electrospray ionization.

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#ionization #electrospray #proteomics #massspectrometry #metabolomics #datascience

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