tobacco

Expanding metabolite coverage of real-time breath analysis by coupling a universal SESI source and a HRMS. A pilot study on tobacco smokers

Expanding metabolite coverage of real-time breath analysis by coupling a universal SESI source and a HRMS. A pilot study on tobacco smokers

M. T. Gaugg, D. Garcia Gomez, C. Barrios-Collado, G. Vidal-de-Miguel, M. Kohler, R. Zenobi and P. M-L Sinues

Coupling a SESI source and a HRMS (Orbitrap), the authors were able to identify exogenous compounds associated to smoking, as well as endogenous metabolites suggesting increased oxidative stress in smokers. According to the authors, most of these compounds correlated significantly with smoking frequency and allowed accurate discrimination of smokers and non-smokers.

Real-Time Chemical Analysis of E-Cigarette Aerosols by Means of Secondary Electrospray Ionization Mass Spectrometry

Real-Time Chemical Analysis of E-Cigarette Aerosols by Means of Secondary Electrospray Ionization Mass Spectrometry

D. Garcia-Gomez, T. Gaisl, C. Barrios-Collado, Guillermo Vidal-de-Miguel, M. Kohler and R. Zenobi

Chemical analysis of aerosols collected from electronic cigarettes (ECs) has shown that these devices produce vapors that contain harmful and potentially harmful compounds. Conventional analytical methods used for the analysis of electronic cigarettes do not reflect the actual composition of the aerosols generated because they usually neglect the changes in the chemical composition that occur during the aerosol generation process and after collection.