Scientific Reports

Comprehensive Real-Time Analysis of the Yeast Volatilome

Comprehensive Real-Time Analysis of the Yeast Volatilome

A. Tejero-Rioseras, D. Garcia-Gomez, B. E. Ebert, L. M. Blank, A. J. Ibanez and P. M-L Sinues

While yeast is one of the most studied organisms, its intricate biology remains to be fully mapped and understood. This is especially the case when it comes to capture rapid, in vivo fluctuations of metabolite levels. According to the authors, the results suggest that a large number of metabolites produced by yeast from glucose neither are reported in the literature nor are their biochemical origins deciphered.

Differentiation of oral bacteria in in vitro cultures and human saliva by secondary electrospray ionization – mass spectrometry

Differentiation of oral bacteria in in vitro cultures and human saliva by secondary electrospray ionization – mass spectrometry

L. Bregy, A. R. Müggler, P. M-L Sinues, D. García-Gómez, Y. Suter, G. N. Belibasakis, M. Kohler, P. R. Schmidlin, Renato Zenobi

The detection of bacterial-specific volatile metabolites may be a valuable tool to predict infection. Here we applied a real-time mass spectrometric technique to investigate differences in volatile metabolic profiles of oral bacteria that cause periodontitis. We coupled a secondary electrospray ionization (SESI) source to a commercial high-resolution mass spectrometer …

Fingerprinting Breast Cancer vs. Normal Mammary Cells by Mass Spectrometric Analysis of Volatiles

Fingerprinting Breast Cancer vs. Normal Mammary Cells by Mass Spectrometric Analysis of Volatiles

Jingjing He, P. M-L Sinues, M. Hollmén, Xue Li, M. Detmar & R. Zenobi

There is increasing interest in the development of noninvasive diagnostic methods for early cancer detection, to improve the survival rate and quality of life of cancer patients. Identification of volatile metabolic compounds may provide an approach for noninvasive early diagnosis of malignant diseases.