Int. J. Mass Spectrometry

Mechanistic study on the ionization of trace gases by an electrospray plume

Mechanistic study on the ionization of trace gases by an electrospray plume

P. M-L Sinues, E. Criado, G. Vidal-de-Miguel

The fact that electrosprays of pure solvents can efficiently ionize gas-phase analytes has been known for decades, although this method has not been widely exploited. With the advent of ambient mass spectrometry, this approach is becoming increasingly popular. However, the mechanism by which vapors become ionized remains largely unknown …

Evaluation of extractive electrospray ionization and atmospheric pressure chemical ionization for the detection of narcotics in breath

Evaluation of extractive electrospray ionization and atmospheric pressure chemical ionization for the detection of narcotics in breath

C. Berchtold, L. Meier, R. Zenobi 

Diagnosis by online breath analysis using mass spectrometry is challenging because of the low concen-trations of pertinent compounds in breath. Here we investigate extractive electrospray ionization and atmospheric pressure chemical ionization for the detection of narcotics in breath.

Mass spectrometric study of cutaneous volatiles by secondary electrospray Ionization

Mass spectrometric study of cutaneous volatiles by secondary electrospray Ionization

P. M-L Sinues

We investigated the volatile organic compounds emanated from the hand of two individuals, on-line by secondary electrospray ionization-mass spectrometry in positive ionization mode. The background ambient air is continuously sampled, ionized and readily mass analyzed. When the probe samples above the headspace of the hand of two subjects, several peaks …