Analytical Methods

Secondary electrospray ionization proceeds via gas-phase chemical ionization

Secondary electrospray ionization proceeds via gas-phase chemical ionization

A. T. Rioseras, M. T. Gaugg and P. M-L Sinues

Our main goal was to gain further insights into the mechanism by which gas-phase analytes are ionized by interaction with plumes of electrospray solvents. We exposed target vapors to electrosprays of either water or deuterated water and mass analyzed them …

In situ detection of γ-hydroxybutyrate and γ-butyrolactone in drinks by secondary electrospray ionization

In situ detection of γ-hydroxybutyrate and γ-butyrolactone in drinks by secondary electrospray ionization

C. Berchtold, S. Schmid, L. Meier and R. Zenobi

γ-Hydroxybutyrate (GHB) and γ-butyrolactone (GBL) are used as “date rape drugs” since they cause catalepsy and memory loss. A new application of secondary electrospray ionization (SESI) mass spectrometry for in situ detection of GHB and GBL in drinks and body fluids is introduced …