Eur. J. Mass Spectrom.

Contribution of liquid-phase and gas-phase ionization in extractive electrospray ionization mass spectrometry of primary amines

Contribution of liquid-phase and gas-phase ionization in extractive electrospray ionization mass spectrometry of primary amines

L. Meier, S. Schmid, C. Berchtold and R. Zenobi

In this study, we investigated how binary mixtures of compounds influence each other's signal intensity in electrospray ionization (ESI), extractive electrospray ionization (EESI) and secondary electrospray ionization (SESI) experiments. The experiments were conducted using a series of homologous primary amines (from 1-butyl to 1- decylamine) …

Manipulation of charge states of biopolymer ions by atmospheric pressure ion/molecule reactions implemented in an extractive electrospray ionization source

Manipulation of charge states of biopolymer ions by atmospheric pressure ion/molecule reactions implemented in an extractive electrospray ionization source

H. Chen, D. Touboul,M. C. Jecklin, J. Zheng, M. Luoa, Renato Zenobid

A home-made extractive electrospray ionization source is coupled to a linear quadrupole ion trap mass spectrometer to investigate ion/molecule reactions of biopolymers at ambient pressure. Multiply charged biopolymers such as peptides and proteins generated in an electrospray are easily reduced to a low charge state by …