As you probably already know, current VOC MS analyzers can detect high volatile species, even when they are present in very low concentrations. For instance, in 2009 P. Spanel and D. Smith measured the concentration of ammonia, acetone, methanol, ethanol, and isoprene in human breath using Selected Ion Flow Tube Mass Spectrometry (SIFT-MS)  .
Sinues is a pioneer of the SESI technology and established SESI-MS as a technique for breath research. The goal in the granted project is to optimize the therapeutic regimen of pediatric patients to maximize efficacy and minimize side effects. For this the group will develop a mass spectrometry-based breath test.