rEAL-TIME ANALYSIS OF VOCS IN EXHALED BREATH

  • We breathe between 17,000 and 30,000 times every day. Each exhalation carries several thousand molecular species that reflect our metabolism in that particular moment.

  • Breath Analysis requires the highest sensitivity and selectivity instruments like SUPER SESI, the lowest detection limits and immediate response.

  • SUPER SESI is non invasive, and can be continuously monitored, offering an excellent window to the human metabolism.

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For more information about the performance of a breath analysis with SUPER SESI, download our Breath Analysis Application Note.

 
 

SCIENTIFIC LITERATURE ON SESI-MS

Real-time breath analysis with SESI-MS is useful for biomarker identification, pharmacokinetic studies and to solve the time dimension in metabolomic studies. Here you are a selection of papers based on Secondary Electro-Spray Ionization (SESI) for the main purposes.

 
 

The field of breath analysis research is very extensive, with several groups working on it. Some areas of interest include:

  • Bio-marker research in Pulmonology & Gastroenterology.

    • Breath comes from the respiratory system, and it is in contact with the oral cavity. It is rich in of lung and gastric metabolites.

    • Some lung problems which could greatly benefit from a breath diagnosis protocol: Pneumonia, TB, COPD, Asthma, Lung Cancer…

  • Bio-markers research of VOCs in blood. The lung exchanges chemical species between blood and breath very efficiently, thus providing access the bloodstream, and the entire body.

  • Human metabolomics.

  • Pharmaco-kinetics. Breath is a non invasive. SUPER SESI allows for the analysis of multiple exhalations without causing any discomfort to the subject. This greatly facilitates the pharmacologic profiling.

 
 
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TIPS TO INCLUDE SUPER SESI IN YOUR BREATH RESEARCH PROTOCOL

A basis breath research plan aimed at the discovery of new breath biomarkers can be categorized as Clinical Study.

We have prepared a free guide to help you prepare the corresponding Clinical Study Protocol to include SUPER SESI.